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MRI in craniofacial fibrous dysplasia
J W Casselman1, I De Jonge, L Neyt
1Department of Radiology, St. Jan Hospital, Bruges, Belgium.
Neuroradiology
|January 1, 1993
Summary
Craniofacial fibrous dysplasia MRI shows varied signal intensities and enhancement patterns. High activity correlates with specific MRI findings, aiding diagnosis.
Area of Science:
- Radiology
- Medical Imaging
- Oncology
Background:
- Craniofacial fibrous dysplasia (CFD) is a rare bone disorder.
- Accurate diagnosis and assessment of disease activity are crucial for patient management.
Purpose of the Study:
- To evaluate the magnetic resonance imaging (MRI) characteristics of craniofacial fibrous dysplasia.
- To correlate imaging findings with histopathological activity.
Main Methods:
- MRI including T1- and T2-weighted sequences and gadolinium-enhanced T1-weighted spin-echo sequence was performed in five patients.
- Histopathological analysis was used to assess lesion activity.
Main Results:
- Lesions typically showed low to intermediate signal intensity on spin-echo sequences.
- All lesions enhanced with gadolinium, but only two became isointense or hyperintense compared to fat.
- High clinical and pathological activity correlated with high signal intensity and strong enhancement in three cases.
Conclusions:
- MRI demonstrates diverse signal intensities and enhancement patterns in craniofacial fibrous dysplasia.
- Specific MRI features may correlate with disease activity, aiding in diagnosis and treatment planning.