Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Botulinum alignment for congenital esotropia

M R Ing

    Ophthalmology
    |March 1, 1993
    PubMed
    Summary

    Botulinum toxin injections for congenital esotropia show less effectiveness in establishing binocularity compared to incisional surgery. Further research is needed to confirm these preliminary findings on motor and sensory outcomes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Congenital esotropia.

    Ophthalmology·2001
    Same author

    Physicians' greatest enemy--complacency!

    Hawaii medical journal·2000
    Same author

    Botulinum toxin therapy in exotropia.

    Ophthalmology·1999
    Same author

    The timing of surgical alignment for congenital (infantile) esotropia.

    Journal of pediatric ophthalmology and strabismus·1999
    Same author

    Needle sterility during strabismus surgery.

    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·1999
    Same author

    Outcome study of bilateral lateral rectus recession for intermittent exotropia in children.

    Ophthalmic surgery and lasers·1999

    Area of Science:

    • Ophthalmology
    • Pediatric Ophthalmology
    • Strabismus Surgery

    Background:

    • Botulinum toxin injection into the medial rectus is proposed as an alternative to surgery for congenital esotropia.
    • Limited data exists on both motor and sensory outcomes for congenital esotropia treated with botulinum toxin.

    Purpose of the Study:

    • To evaluate the motor and sensory results of congenital esotropic patients aligned with botulinum toxin.
    • To compare the efficacy of botulinum toxin alignment versus incisional surgery for congenital esotropia.

    Main Methods:

    • Twelve patients with congenital esotropia, aligned by botulinum toxin before age 2, were examined using standardized methods.
    • Patients were followed for at least 3 years, with assessments of motor alignment and sensory function (fusion, stereopsis).
    • Results were compared to previously published data on surgically aligned congenital esotropia cases.

    Main Results:

    • Only 6 of 12 patients achieved optimal motor alignment (within 10 prism diopters) 1-5 months post-injection.
    • Of the aligned patients, only 3 demonstrated fusion and stereopsis without prisms.
    • Surgically aligned patients showed significantly better rates of fusion and stereopsis (66/90).

    Conclusions:

    • Botulinum toxin alignment appears less effective than incisional surgery for achieving binocularity in congenital esotropia.
    • These preliminary findings suggest surgery may be superior for long-term visual function.
    • Further investigation is warranted to confirm these outcomes.

    Related Experiment Videos