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Cytokines and cancer cachexia
1University of Texas, Dallas.
Hospital Practice (Office Ed.)
|April 15, 1993
Abstract:
A by-product of cancer (and of other chronic diseases or severe trauma), cachexia appears to be mediated by various cytokines. The first to be identified--tumor necrosis factor--may be a principal mediator. With molecular cloning techniques, future treatment strategies could include blockade of TNF activity using highly specific reagents.