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[Pregnancy and non-Hodgkin's lymphoma: a case]

P Morice1, B Cristalli, M Heid

  • 1Service de Chirurgie Gynécologique et d'Obstétrique, Hôpital Beaujon, Clichy.

Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction
|January 1, 1993
PubMed
Summary

This case study details a rare malignant non-Hodgkin lymphoma complicating pregnancy. Despite treatment, both mother and infant experienced fatal outcomes, highlighting poor prognosis for lymphoma during pregnancy.

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Area of Science:

  • Oncology
  • Obstetrics & Gynecology
  • Hematology

Background:

  • Non-Hodgkin lymphoma (NHL) is a rare complication during pregnancy.
  • Malignant lymphomas during pregnancy pose significant diagnostic and therapeutic challenges.
  • Limited literature exists on the management and outcomes of pregnancy-associated lymphomas.

Observation:

  • A 19-year-old pregnant woman presented with malignant non-Hodgkin lymphoma.
  • The lymphoma's progression was rapid and unfavorable despite corticotherapy.
  • The case involved premature birth followed by maternal and infant mortality.

Findings:

  • Corticosteroid treatment led to a rapidly unfavorable clinical course.
  • Premature delivery resulted in neonatal death within 24 hours.

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  • Maternal death occurred 48 hours post-delivery despite chemotherapy attempts.

    • Implications:

    • Pregnancy-associated lymphomas carry a grave prognosis for both mother and fetus.
    • Fetal risks include premature delivery and associated complications.
    • Maternal risks involve aggressive tumor progression, particularly postpartum.