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Mucormycosis of the oral cavity
A C Jones1, T Y Bentsen, P D Freedman
1Department of Oral Diagnostic Sciences, University of Florida College of Dentistry.
Abstract:
Mucormycosis (phycomycosis, zygomycosis) is an acute opportunistic infection caused by a saprophytic fungus found in soil, bread molds, and decaying fruits and vegetables. Numerous predisposing risk factors are associated with mucormycosis, although most cases have been reported in poorly controlled diabetics or in patients with hematologic malignant conditions. This report presents two cases of oral mucormycosis. One case occurred in the maxilla in a patient with well-controlled diabetes. The other involved the mandible and overlying gingiva in a patient with acute myelogenous leukemia. A review of the literature concerning oral mucormycosis is also presented.
Insights
Mucormycosis is a serious fungal infection. This study details two oral mucormycosis cases, one in a diabetic patient and another with leukemia, highlighting varied risk factors for this opportunistic infection.
Area of Science:
- Mycology
- Infectious Diseases
- Oral Pathology
Background:
- Mucormycosis is an acute, opportunistic fungal infection caused by saprophytic fungi.
- Commonly associated with uncontrolled diabetes and hematologic malignancies.
- Found in soil, bread molds, and decaying organic matter.
Observation:
- Presents two distinct cases of oral mucormycosis.
- Case 1: Maxillary mucormycosis in a patient with well-controlled diabetes.
- Case 2: Mandibular and gingival mucormycosis in a patient with acute myelogenous leukemia.
Findings:
- Oral mucormycosis can occur in patients with seemingly controlled risk factors.
- Demonstrates the varied clinical presentations of oral mucormycosis.
- Highlights the importance of considering mucormycosis in immunocompromised patients.
Implications:
- Emphasizes the need for prompt diagnosis and management of oral mucormycosis.
- Suggests that even well-controlled diabetes may not preclude opportunistic infections.
- Underscores the diverse etiologies and presentations of this severe fungal infection.