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[Non-typhoid Salmonella aortitis]

O Brubakk1, J N Bruun

  • 1Medisinsk avdeling Ostfold Sentralsykehus, Sarpsborg.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|February 10, 1993
PubMed
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Non-typhoid Salmonella enteritis can lead to aortitis. Surgical intervention combined with long-term antibiotics offers a better survival rate for Salmonella aortitis compared to antibiotic treatment alone.

Area of Science:

  • Infectious Diseases
  • Cardiovascular Surgery
  • Medical Microbiology

Background:

  • Non-typhoid Salmonella enteritis is a potential cause of serious complications.
  • Aortitis, an inflammation of the aorta, can be a rare but severe sequela of Salmonella infections.

Purpose of the Study:

  • To describe cases of Salmonella enteritidis aortitis.
  • To evaluate treatment outcomes for Salmonella aortitis.
  • To highlight diagnostic and therapeutic strategies for this condition.

Main Methods:

  • Case series describing three patients with Salmonella enteritidis aortitis.
  • Review of diagnostic methods including blood cultures and imaging (CT-scanning, ultrasonography, angiography).
  • Comparison of treatment approaches: surgery with antibiotics versus antibiotics alone.

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Main Results:

  • One patient survived after aortic resection, axillo-femoral bypass, and 18 months of antibiotics.
  • Two patients treated solely with antibiotics did not survive.
  • Diagnosis was confirmed via blood cultures and detailed aortic imaging.

Conclusions:

  • Salmonella aortitis requires a multimodal treatment approach.
  • Combination therapy of surgery and prolonged antibiotic administration is crucial for improved survival.
  • Early diagnosis through appropriate imaging and cultures is vital for effective management.