Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Superantigens of microbial origin

V V Micusan1, J Thibodeau

  • 1Centre de recherche en immunologie, Institut Armand-Frappier, Université du Québec, Ville de Laval, Canada.

Seminars in Immunology
|February 1, 1993
PubMed
Summary

Staphylococcal enterotoxins, a type of superantigen, are key in immunological research. These bacterial toxins significantly impact T cell functions, potentially leading to bacterial and autoimmune diseases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Novel paradigm enables accurate monthly gestational screening to prevent congenital toxoplasmosis and more.

medRxiv : the preprint server for health sciences·2023
Same author

Purification and identification of bovine cheese whey fatty acids exhibiting in vitro antifungal activity.

Journal of dairy science·2008
Same author

Molecular analysis of Desulfitobacterium frappieri pcp-1 involved in reductive dehalogenation of pentachlorophenol.

Water science and technology : a journal of the International Association on Water Pollution Research·2005
Same author

Class II transactivator-induced expression of HLA-DO(beta) in HeLa cells.

Tissue antigens·2002
Same author

Validity and reliability of simple nutrition screening tools adapted to the elderly population in healthcare facilities.

The journal of nutrition, health & aging·2001
Same author

Quantitative relationship between MHC class II-superantigen complexes and the balance of T cell activation versus death.

Journal of immunology (Baltimore, Md. : 1950)·2001

Area of Science:

  • Immunology
  • Microbiology
  • Toxicology

Background:

  • Bacterial products like staphylococcal enterotoxins are recognized for their unique properties.
  • These properties classify them as superantigens, substances with significant immunological impact.

Purpose of the Study:

  • To review the role of staphylococcal enterotoxins as representative superantigens.
  • To highlight their influence on T cell functions and potential link to diseases.

Main Methods:

  • Literature review focusing on immunological research of bacterial products.
  • Analysis of superantigen properties and their effects on T cells.

Main Results:

  • Superantigens, exemplified by staphylococcal enterotoxins, modulate T cell repertoire and cytokine production.
  • These modulations can lead to altered immune responses.

Conclusions:

  • Superantigens possess the potential to cause bacterial and autoimmune diseases.
  • Staphylococcal enterotoxins serve as a primary model for understanding superantigen mechanisms.

Related Experiment Videos