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Graft failure following neutrophil-specific alloantigen mismatched allogeneic BMT
T R Klumpp1, J H Herman, K F Mangan
1Bone Marrow Transplantation Program, Temple University Comprehensive Cancer Center, Philadelphia, PA 19140.
Bone Marrow Transplantation
|March 1, 1993
Abstract:
We report a case of unexplained graft failure in a 33-year-old man who received an allogeneic bone marrow graft that contained a donor-recipient mismatch involving the highly immunogenic NA1 neutrophil-specific alloantigen system. Laboratory and clinical data suggest that an alloimmune process related to the neutrophil alloantigen mismatch played a role in the development of the graft failure.