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Systemic sclerosis following anti-androgenic treatment for prostatic adenocarcinoma
N Giordano1, L Magaro, L Fattorini
1Institute of Rheumatology, University of Siena, Italy.
Clinical Rheumatology
|March 1, 1993
Abstract:
We describe a male patient who developed systemic sclerosis following orchiectomy, radiotherapy and anti-androgenic treatment for prostatic adenocarcinoma. This case appears interesting as it further supports the possibility of a relationship between neoplasia and systemic sclerosis. The concurrence of scleroderma and iatrogenic hypoandrogenism suggests that hormonal influences may also play a role in the pathogenesis of this connective tissue disorder.