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[A case of Down's syndrome with progressive dementia of Alzheimer type]
1Department of Radiology, University of Occupational and Environmental Health, School of Medicine.
Kaku Igaku. the Japanese Journal of Nuclear Medicine
|February 1, 1993
Abstract:
A rare case of Down's syndrome complicated with progressive dementia of Alzheimer type in a 41-year-old man was reported. On 123I-IMP SPECT, the patient revealed symmetrical bilateral temporo-parietal hypoperfusion. This finding seemed to support the developing dementia of Alzheimer type on the basis of clinical manifestations. 123I-IMP SPECT seemed to be useful for early diagnosis of Alzheimer-like change in a natural course of Down's syndrome.