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Preliminary experience with a modified Tenckhoff catheter for intraperitoneal chemotherapy
H N Nguyen1, H E Averette, L Wyble
1Division of Gynecologic Oncology, University of Miami School of Medicine, FL 33101.
Journal of Surgical Oncology
|April 1, 1993
Summary
This study evaluated a modified Tenckhoff catheter for intraperitoneal chemotherapy in ovarian cancer patients. While complications were observed, the modified catheter showed potential, though further research is needed.
Area of Science:
- Oncology
- Surgical Devices
- Medical Engineering
Background:
- Intraperitoneal chemotherapy is a treatment for ovarian cancer.
- Tenckhoff catheters are used for delivering chemotherapy intraperitoneally.
- Previous catheter designs have limitations.
Purpose of the Study:
- To report preliminary experience with a modified Tenckhoff catheter.
- To assess the safety and efficacy of the modified catheter for intraperitoneal chemotherapy.
- To compare complication rates with existing catheter systems.
Main Methods:
- A modified Tenckhoff catheter, larger with more perfusion holes, was implanted in 125 ovarian cancer patients.
- 116 catheters were used for 559 cycles of intraperitoneal chemotherapy.
- Complications including infection, obstruction, perforation, and leakage were recorded.
Main Results:
- Seven infections (6.0%), four inflow obstructions (3.4%), three bowel perforations (2.6%), and one leakage (0.8%) were reported.
- Inflow obstruction incidence decreased but not significantly.
- Delayed bowel perforation occurred in three patients with catheter infections.
Conclusions:
- The modified Tenckhoff catheter demonstrated a comparable complication profile to existing catheters.
- Early removal of unused catheters is crucial to prevent serious complications like bowel perforation.
- Further investigation is required to fully ascertain the performance of this modified catheter system.