Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human intestinal methanogens and lactulose administration

A Rutili1, T Brusa, E Canzi

  • 1Department of Food Science and Microbiology, University of Milan, Italy.

The New Microbiologica
|January 1, 1993
PubMed
Summary

Lactulose therapy did not significantly alter human intestinal methanogen populations. Methanogens were prevalent in both treated and control groups, with wide variations in numbers observed.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinically equivocal melanocytic skin lesions with features of regression: a dermoscopic-pathological study.

The British journal of dermatology·2004
Same author

On the conversion coefficients for cosmic ray dosimetry.

Radiation protection dosimetry·2003
Same author

Preliminary studies on compatibility between high yield levels and the well-being of dairy cows.

Veterinary research communications·2003
Same author

Advanced ovarian carcinoma: usefulness of [(18)F]FDG-PET in combination with CT for lesion detection after primary treatment.

The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR)·2003
Same author

Emerging problems in the pharmacology of migraine: interactions between triptans and drugs for prophylaxis.

Pharmacological research·2003
Same author

Estimating mixed field effects: an application supporting the lack of a non-linear component for chromosome aberration induction by neutrons.

Radiation protection dosimetry·2003

Area of Science:

  • Microbiology
  • Gastroenterology

Background:

  • Methanogenic archaea are key components of the human gut microbiota.
  • Lactulose is a synthetic disaccharide used to treat constipation and hepatic encephalopathy.

Purpose of the Study:

  • To evaluate the effect of lactulose therapy on the abundance of human intestinal methanogens.

Main Methods:

  • Quantification of methanogens in fecal samples from ten lactulose-treated subjects and ten healthy controls.
  • Statistical analysis using analysis of variance (ANOVA).

Main Results:

  • Methanogens were detected in 90% of all subjects (9 treated, 9 controls).
  • A broad range of methanogen counts (10^3–10^10 cells/gdw) was observed in both groups.

Related Experiment Videos

  • No statistically significant difference in methanogen numbers was found between lactulose-treated and control groups.

    • Conclusions:

    • Lactulose therapy does not appear to significantly impact the overall number of intestinal methanogens in humans.
    • Further research may be needed to explore potential effects on specific methanogen species or functional roles.