Related Experiment Videos
Pregnancy complicated by Gorham disease
K B Porter1, W F O'Brien, G Towsley
1Department of Obstetrics and Gynecology, University of South Florida College of Medicine, Tampa.
Background:
A pregnancy with Gorham disease (massive osteolysis syndrome) is described. To our knowledge, this is the first reported case of a pregnancy associated with this disease.
Case:
A 25-year-old woman was seen for pre-conception counseling with the diagnosis of Gorham disease. Before pregnancy, magnetic resonance imaging confirmed a stable disease process. The woman and fetus were followed during pregnancy with ultrasound and consultations. Severe preeclampsia developed at delivery, with a significant thrombocytopenia. We delivered the infant by low forceps, with a good outcome. Subsequently, the mother and child were doing well at 18 months postpartum.
Conclusion:
We briefly review this rare bone disease as it relates to pregnancy and provide information for preconception counseling.