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Endodermal sinus (yolk sac) tumor of vagina and cervix in an infant
1Department of Radiology, Medical College and Hospital, National Taiwan University, Taipei, Republic of China.
Insights
A rare vaginal and cervical endodermal sinus tumor occurred in a 6-month-old infant. This yolk sac tumor presented with bloody discharge and was confirmed through imaging and histopathology.
Area of Science:
- Gynecologic Oncology
- Pediatric Oncology
- Pathology
Background:
- Endodermal sinus tumors (yolk sac tumors) are rare germ cell tumors.
- These tumors can occur in various locations, including the vagina and cervix.
- Pediatric gynecologic malignancies are uncommon, necessitating case reports for understanding.
Observation:
- A 6-month-old female infant presented with intermittent bloody discharge.
- Pelvic CT revealed an irregular, enhancing mass in the vagina and cervix.
- The mass exhibited characteristics consistent with a malignant soft tissue tumor.
Findings:
- Histopathologic examination confirmed the diagnosis of endodermal sinus tumor.
- The tumor involved both the vaginal and cervical tissues.
- The findings were consistent with a yolk sac tumor of the female reproductive tract.
Implications:
- This case highlights the importance of considering rare gynecologic malignancies in infants.
- Early diagnosis and appropriate management are crucial for improving outcomes in pediatric patients.
- Further research into the etiology and treatment of pediatric endodermal sinus tumors is warranted.
Abstract:
A case of vaginal and cervical endodermal sinus (yolk sac) tumor in a 6-month-old female infant is reported. The patient presented with an intermittent bloody discharge on her diapers. Pelvic CT showed an irregular soft tissue density mass with heterogeneous enhancement within the vagina and extending to the cervix. The histopathologic features were identical to those of endodermal sinus tumors.