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Darrow-Gamble disease: ultrasonographic and radiographic findings
C Poggiani1, A Auriemma, P Menghini
1Neonatal Intensive Care Unit, Ospedali Riuniti, Bergamo, Italy.
Abstract:
A case of Darrow-Gamble disease is presented with review of the radiographic and ultrasonographic appearance of this rare cause of profound chronic diarrhea beginning at birth. The disease is caused by a defect of active intestinal chloride transport which results in a large loss of the electrolytes and water. To prevent growth retardation and renal involvement an adequate replacement therapy is necessary. This uncommon anomaly was detected by ultrasound 3 weeks before delivery. Both sonography and radiography were useful diagnostic tools in the postnatal period. The clinical features of the lesion are also discussed.
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