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[The radioprotective effect of GABA-tropic substances, gamma-hydroxybutyrate and piracetam]
Radiobiologiia
|January 1, 1993
Abstract:
From experiments in mice, it is shown that with a radiation dose of 8 Gy (LD96) the radioprotective effect was exerted by gamma-aminobutyric acid (GABA), substances that increase its concentration in tissues (progabide and valproate), and synthetic agonists of both receptor types, particularly baclofen, a GABA-receptor agonist. The radioprotective effect is also exerted by gamma-hydroxybutyrate, not piracetam.