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Peritonitis rates in CAPD patients using the UVXD and O-set systems
G R Bailie1, R Rasmussen, G Eisele
1Department of Pharmacy Practice, Albany College of Pharmacy, New York.
Renal Failure
|January 1, 1993
Summary
The O-set system showed a significantly lower peritonitis rate compared to the UVXD system in patients undergoing dialysis. UVXD patients experienced peritonitis more frequently, indicating O-set may offer better protection against this complication.
Area of Science:
- Nephrology
- Medical Devices
- Infectious Diseases
Background:
- Peritonitis is a significant complication in patients undergoing peritoneal dialysis.
- Comparing the efficacy of different dialysis systems in preventing peritonitis is crucial for patient outcomes.
Purpose of the Study:
- To compare the incidence and characteristics of peritonitis between the O-set and UVXD dialysis systems.
- To evaluate the peritonitis-free period and relapse rates in patients using these two systems.
Main Methods:
- A retrospective study comparing 69 patients on the O-set system with 54 patients on the UVXD system.
- Data collected included patient demographics, dialysis duration, peritonitis episodes, causative organisms, and relapse rates.
- Statistical analysis included Z-tests to compare peritonitis rates.
Main Results:
- The UVXD system had a significantly higher peritonitis rate (1 episode per 7.4 months) compared to the O-set system (1 episode per 10.7 months) (p = 0.032).
- The odds ratio for peritonitis was 1:1.85 (O-set:UVXD), with UVXD showing a higher risk.
- While the time to first peritonitis and peritonitis-free periods were similar, the overall peritonitis rate differed significantly between the systems.
Conclusions:
- The O-set system appears to be associated with a lower peritonitis rate compared to the UVXD system.
- Further research may be warranted to understand the factors contributing to the difference in peritonitis rates between these dialysis systems.