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Related Experiment Videos

[Does drinking protect against mountain sickness?]

P Bärtsch1, S Shaw, P Weidmann

  • 1Medizinische Klinik und Poliklinik, Universität Heidelberg.

Schweizerische Zeitschrift Fur Sportmedizin
|March 1, 1993
PubMed
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Fluid intake does not prevent acute mountain sickness (AMS) or high altitude pulmonary edema (HAPE). Mountaineers with AMS exhibit reduced water and salt excretion, potentially due to hormonal changes.

Area of Science:

  • Altitude Medicine
  • Physiology

Context:

  • Ascent to high altitudes (4559 m) poses physiological challenges.
  • Acute mountain sickness (AMS) and high altitude pulmonary edema (HAPE) affect a significant portion of mountaineers.

Purpose:

  • To investigate fluid balance and hormonal responses in individuals experiencing AMS and HAPE.
  • To determine the role of fluid intake and hormonal factors in the development of altitude-related illnesses.

Summary:

  • 57 mountaineers were studied during ascent; 24 developed AMS and 16 HAPE.
  • Individuals with AMS showed decreased diuresis and natriuresis, irrespective of fluid intake (2-4 L/24h).
  • Elevated aldosterone and vasopressin levels may contribute to fluid and salt retention in AMS.

Impact:

Related Experiment Videos

  • Higher fluid intake increases urine output but does not prevent AMS.
  • Findings suggest hormonal dysregulation may play a key role in AMS pathophysiology.
  • Further research is needed to clarify if hormonal changes are a cause or consequence of hypoxemic stress.