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Updated: Aug 6, 2026

Teratoma Generation in the Testis Capsule
Published on: November 7, 2011
Congenital adrenal hyperplasia with testicular tumors, aggression, and gonadal failure
E J Keely1, I Matwijiw, J A Thliveris
1Department of Medicine, University of Manitoba, Winnipeg, Canada.
Abstract:
Bilateral testicular tumors (adrenal rests) may occur in untreated or poorly controlled congenital adrenal hyperplasia. This case report describes two unique associated phenomena: (1) psychologic disturbances similar to those seen with exogenous androgen abuse, which resolved with appropriate glucocorticoid suppression of androgen over-production by this abnormal adrenal/adrenal rest tissue; and (2) testicular failure which showed a partial, delayed recovery with corticosteroid therapy. The need for a careful history and biochemical screening for all patients with bilateral testicular tumors is reinforced.
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