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Related Experiment Videos

The effect of compression on venous stasis

P M Gaylarde1, I Sarkany, H J Dodd

  • 1Department of Dermatology, Royal Free Hospital, Hampstead, London, U.K.

The British Journal of Dermatology
|March 1, 1993
PubMed
Summary

External compression bandages effectively increase leg skin oxygenation in standing individuals, preventing hypoxia. Lightweight stockings are recommended for preventing deep-vein thrombosis in bedridden patients.

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Area of Science:

  • Physiology
  • Vascular Medicine
  • Biomedical Engineering

Background:

  • Prolonged standing can lead to lower leg hypoxia due to reduced blood flow.
  • Venous ulcers and deep-vein thrombosis (DVT) are significant clinical concerns.
  • The role of external compression in modulating skin oxygenation is not fully elucidated.

Purpose of the Study:

  • To investigate the effects of external compression on skin blood flow and oxygen tension in the lower leg.
  • To determine optimal compression pressures for preventing hypoxia in standing subjects.
  • To evaluate the safety and efficacy of different compression levels for DVT prophylaxis.

Main Methods:

  • Measurements of skin blood flow and transcutaneous oxygen tension (TcP O2) were taken.
  • Subjects were subjected to varying levels of external compression (0-50 mmHg) in both standing and recumbent positions.
  • Different types of compression devices, including elastic stockings and bandages, were tested.

Main Results:

  • External compression significantly increased skin blood flow and TcP O2 in standing subjects, with maximal effects observed at 40-50 mmHg.
  • Lightweight elastic stockings (producing <10 mmHg) were ineffective in improving oxygenation.
  • In recumbent subjects, external compression above 10 mmHg led to a decrease in TcP O2.

Conclusions:

  • High-pressure compression (40-50 mmHg) is effective in preventing standing-induced hypoxia and supports clinical use for venous ulcers.
  • Lightweight compression stockings are safe and appropriate for DVT prophylaxis in recumbent patients.
  • Avoidance of high external pressure (>10 mmHg) is crucial for preventing complications in immobilized patients.

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