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Resection of presumed benign liver tumours
J Belghiti1, D Pateron, Y Panis
1Digestive Surgery Unit, Hôpital Beaujon, Clichy-Paris, France.
The British Journal of Surgery
|March 1, 1993
Summary
Surgical resection of presumed benign liver tumors in young women is safe, even with uncertain preoperative diagnosis. This approach helps identify unexpected malignant lesions and ensures accurate pathological confirmation.
Area of Science:
- Hepatobiliary surgery
- Surgical oncology
- Diagnostic imaging
Background:
- Surgical treatment for benign liver tumors like focal nodular hyperplasia (FNH) and hepatic adenoma is debated.
- Accurate preoperative diagnosis of these lesions can be challenging.
Purpose of the Study:
- To compare preoperative diagnoses with final pathological findings for presumed benign liver tumors.
- To evaluate the justification and safety of surgical intervention.
Main Methods:
- Retrospective analysis of 51 women under 50 undergoing tumor resection between 1984-1990.
- Preoperative assessment included liver function tests, ultrasonography, dynamic CT, and advanced imaging (angiography, MRI, scintigraphy).
Main Results:
- Final pathological diagnosis confirmed FNH in 71%, hepatic adenoma in 24%, and malignant lesions in 6%.
- Malignant lesions included hepatocellular carcinoma and fibrolamellar carcinoma.
- No postoperative deaths or serious complications occurred.
Conclusions:
- Precise preoperative diagnosis of benign liver tumors remains difficult.
- Malignant liver tumors may be missed preoperatively.
- Resection is a safe and effective treatment for these lesions, especially when FNH diagnosis is uncertain.