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Trace element concentrations (Cu, Zn, Fe) in sera from patients with dilated cardiomyopathy
1Institut für Klinische Chemie und Laboratoriumsmedizin, Universitätsklinik Mainz, Germany.
Clinica Chimica Acta; International Journal of Clinical Chemistry
|February 28, 1993
Abstract:
The trace element concentrations (Cu, Zn, Fe) in sera from patients with dilated cardiomyopathy are reported. Patients with dilated cardiomyopathy have high copper and low zinc concentrations in serum compared to healthy controls. The trace element concentration profile is different from that of other heart diseases like myocardial infarction and coronary heart disease. The copper concentration in serum shows a highly significant inverse relationship with the ejection fraction and the cardiac index. Pathophysiological processes which raise the copper concentration in serum may influence the ejection fraction and the cardiac index.