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Related Experiment Videos

[Ocular involvement in rheumatoid arthritis]

A Bogliolo1, Q Mela, L Perpignano

  • 1I Cattedra di Reumatologia, Università degli Studi di Cagliari.

La Clinica Terapeutica
|January 1, 1993
PubMed
Summary

Rheumatoid arthritis (RA) patients show low rates of ocular issues like dry eye and cataracts. However, fluorescein angiography can detect silent retinal vasculitis in active RA cases.

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Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Context:

  • Rheumatoid arthritis (RA) is a systemic autoimmune disease.
  • Ocular manifestations can occur in RA patients.
  • Assessing ocular involvement is crucial for comprehensive RA management.

Purpose:

  • To evaluate the prevalence and types of ocular involvement in RA patients.
  • To identify subclinical ocular disease using diagnostic tools like fluorescein angiography.
  • To assess drug-induced ocular toxicity in RA patients.

Summary:

  • Twenty-three RA patients were assessed for ocular involvement.
  • Low prevalence of keratoconjunctivitis sicca (4%) and high rate of positive Schirmer tests (26%) were observed.
  • Fluorescein angiography detected subclinical retinal vasculitis in 18% of examined patients, suggesting its utility in active RA.

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  • Ocular drug toxicity was rare, with only one case of steroid-induced cataract (4%).

    • Impact:

    • Highlights the importance of routine ocular screening in RA patients.
    • Suggests fluorescein angiography as a valuable tool for detecting silent retinal vasculitis in specific RA subgroups.
    • Provides data on the low incidence of ocular toxicity from common RA medications.