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[Clinical study of children with nasal allergy]
K Morimoto1, H Saito, S Narita
1Department of Otolaryngology, Ebetsu Municipal Hospital.
Insights
This study identifies key indicators for diagnosing nasal allergies in children, including eosinophil counts and IgE RAST scores. Bottle feeding and asthma history were linked to definite allergy cases.
Area of Science:
- Pediatric Allergy and Immunology
- Clinical Diagnostics
- Epidemiology
Context:
- Nasal allergy prevalence in children necessitates accurate diagnostic methods.
- Identifying reliable predictors for pediatric allergic rhinitis is crucial for timely intervention.
- Existing diagnostic tools require validation for specific pediatric populations.
Purpose:
- To evaluate the predictive value of specific allergic markers for nasal allergy in children.
- To identify clinical and epidemiological factors associated with confirmed pediatric nasal allergy.
- To establish diagnostic criteria for allergic rhinitis in pediatric patients.
Summary:
- A study involving 196 children assessed nasal allergy using questionnaires, eosinophil counts, IgE RAST scores for house dust, and provocation tests.
- The definite allergy group showed high predictive values for eosinophil count (77.0%), IgE RAST score (89.2%), and provocation tests (78.1%).
- Bottle feeding and a history of asthma bronchiale were more frequent in children with definite nasal allergies.
Impact:
- Provides evidence-based diagnostic parameters for pediatric allergic rhinitis.
- Highlights potential risk factors like bottle feeding and asthma history in childhood nasal allergies.
- Supports the development of targeted diagnostic strategies and management plans for pediatric allergic rhinitis.
Abstract:
Possible factors influencing nasal allergy in children were studied using a questionnaire and allergic examination including eosinophil count of nasal discharge, IgE RAST score to house dust and provocation test. We investigated three groups of children according to the results of allergic examinations. The negative group, the equivocal group and the definite group, respectively, consisted of 40, 49 and 107 children. We found the prediction value of definite group with eosinophil count of nasal discharge, IgE-RAST score and provocation test to house dust were respectively 77.0, 89.2 and 78.1%. Bottle feeding and history of asthma bronchiale occurred more frequently in the definite group. These observations provide epidemiologic and clinical bases for further investigations of children with nasal allergy.