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Familial systemic lupus erythematosus characterized by digital ischemia
J T Sibley1, K L Blocka, D P Sheridan
1Department of Medicine, University of Saskatchewan, Saskatoon, Canada.
The Journal of Rheumatology
|February 1, 1993
Abstract:
We describe a family in which 3 members each developed systemic lupus erythematosus complicated by ischemic vasculopathy. The calendar years and patient ages of disease onset and the clinical courses were remarkably similar for all 3 patients, although their genotypes were not. The potential contributions of heredity and environment to the concordance of disease expression in this family are discussed.