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Antenatal cerebral necrosis in monochorionic twins
1Department of Pathology, UCSD Medical Center 92103.
Pediatric Pathology
|January 1, 1993
Summary
Monochorionic twins face risks of antenatal cerebral white matter necrosis. Shared placental vessels may cause hemodynamic instability, leading to brain injury in both fetuses.
Area of Science:
- Neonatal neurology
- Perinatal medicine
- Twin gestation studies
Background:
- Antenatal cerebral white matter necrosis is a known complication in monochorionic twins.
- It is often associated with twin-twin transfusion syndrome or demise of one twin.
Observation:
- Presents a case of antenatal cerebral necrosis in both liveborn monochorionic twins.
- No twin demise or blood-borne factor transfer was observed.
Findings:
- Proposes placental artery-to-artery or vein-to-vein anastomoses as a predisposing factor.
- Suggests hemodynamic instability due to blood pressure or volume fluctuations can cause cerebral necrosis.
Implications:
- Highlights a potential mechanism for cerebral necrosis in surviving monochorionic twins.
- May inform strategies for monitoring and managing hemodynamic risks in twin pregnancies.