Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Memory for visuospatial patterns in Alzheimer's disease

D Grossi1, J T Becker, C Smith

  • 1Neurologic Institute, 2nd Medical School, Naples, Italy.

Psychological Medicine
|February 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Does primary Streptococcus viridans pneumonia exist?

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·1992
Same author

Acyl-CoA:cholesterol O-acyl transferase (ACAT) inhibitors. 1. 2-(Alkylthio)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT.

Journal of medicinal chemistry·1992
Same author

Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite.

Archives of biochemistry and biophysics·1992
Same author

Acupuncture: an ancient treatment modality under scientific scrutiny.

Journal of the American Veterinary Medical Association·1992
Same author

Evaluation of new anti-infective drugs for the treatment of infective endocarditis. Infectious Diseases Society of America and the Food and Drug Administration.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·1992
Same author

Screening for alpha-thalassemia. Correlation of hemoglobin H inclusion bodies with DNA-determined genotype.

Archives of pathology & laboratory medicine·1992
Same journal

Replicable subcortical alterations linked to neurological soft signs in schizophrenia spectrum disorders.

Psychological medicine·2026
Same journal

Distinct and common subcortical functional connectivity revealed across three major psychiatric disorders - CORRIGENDUM.

Psychological medicine·2026
Same journal

Adversity as the key feature: neuroimaging profiles of subtypes from multiple depression risk factors.

Psychological medicine·2026
Same journal

Sorting the mind: cognitive enhancement through transcutaneous auricular vagus nerve stimulation: a systematic review and meta-analysis.

Psychological medicine·2026
Same journal

Depression and aging: insights from brain age prediction models.

Psychological medicine·2026
Same journal

An integrative NLP framework identifies multilevel linguistic phenotypes of schizophrenia across tasks.

Psychological medicine·2026
See all related articles

Alzheimer's dementia patients show specific visual working memory deficits. This impairment affects the visuospatial scratchpad, impacting immediate memory for visual patterns.

Area of Science:

  • Neuropsychology
  • Cognitive Neuroscience
  • Dementia Research

Background:

  • Alzheimer's disease (AD) is a progressive neurodegenerative disorder.
  • Cognitive deficits in AD often include memory impairment.
  • Visuospatial functions are crucial for daily activities and cognitive assessment.

Purpose of the Study:

  • To investigate immediate memory for visuospatial information in Alzheimer's-type dementia patients with preserved visuo-perceptual abilities.
  • To determine if Alzheimer's dementia specifically affects the visuospatial component of working memory.

Main Methods:

  • Two visuospatial memory tasks were administered: Corsi's block tapping test and a novel pattern memory task.
  • The study involved parallel groups of Alzheimer's patients and healthy controls in Italy and the United States.

Related Experiment Videos

  • Performance was compared between patient and control groups across tasks.

    • Main Results:

    • Alzheimer's patients exhibited a specific deficit in immediate visual working memory.
    • This deficit was evident even on tasks where control subjects performed without errors.
    • The impairment suggests a targeted impact on visuospatial processing within working memory.

    Conclusions:

    • The findings support the Working Memory Model, indicating potential impairment of the Visuospatial Scratchpad in Alzheimer's dementia.
    • Unlike verbal subsystems, the visuospatial scratchpad may be particularly vulnerable in the early stages of dementia.
    • This highlights a specific cognitive domain affected by Alzheimer's disease.