Dependence between apolipoprotein E phenotypes and temperament in children, adolescents, and young adults
L Keltikangas-Järvinen1, K Räikkönen, T Lehtimäki
1Department of Psychology, University of Helsinki, Finland.
Abstract:
The association of apolipoprotein E (apoE) polymorphism with temperament and Type A behavior was studied in 1577 randomly selected healthy children, adolescents, and young adults during a follow-up period of 9 years. Temperament was correlated with apoE phenotypes. Motor activity, even hyperactivity, in childhood and mental vitality in adolescence and young adulthood increased significantly with the apoE phenotypes in the order of E2/2, E3/2, E4/2, E3/3, E4/3, and E4/4. However, global Type A behavior was not associated with the order of apoE phenotypes. The findings suggest the importance of additional studies on genetic factor and temperament.
Related Concept Videos
Personality Theory by Eysenck and Eysenck
In the extroversion/introversion dimension, highly extroverted people are sociable, outgoing, and easily connect with others. In contrast,...
Socioemotional Development during Infancy
Primary Temperament Types
Stella Chess...
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Adler's Individual Psychology
Background and Environment Affect Phenotype
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase


