Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Familial calculous cholecystopathy]

S J Cano1

  • 1Servicio de Medicina Interna en el Hospital del Seguro Social en la ciudad de Panamá.

Revista Medica De Panama
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Traceability and comparability through crosswalks with the NeuroMET Memory Metric.

Scientific reports·2023
Same author

Proxy reporting of health-related quality of life for people with dementia: a psychometric solution.

Health and quality of life outcomes·2020
Same author

Development of a new patient-reported outcome measure to evaluate treatments for acne and acne scarring: the ACNE-Q.

The British journal of dermatology·2019
Same author

The FACE-Q Skin Cancer Module addresses post-resection aesthetic and quality of life outcomes.

The British journal of dermatology·2018
Same author

FACE-Q Skin Cancer Module for measuring patient-reported outcomes following facial skin cancer surgery.

The British journal of dermatology·2018
Same author

Development and validation of a generic scale for use in transition programmes to measure self-management skills in adolescents with chronic health conditions: the TRANSITION-Q.

Child: care, health and development·2014

Gallstones (cholelithiasis) and associated conditions like obesity and diabetes appear to run in families, affecting multiple generations. This suggests a potential genetic or shared environmental influence on the development of these common health issues.

Area of Science:

  • Gastroenterology and Genetics
  • Metabolic Diseases
  • Epidemiology

Context:

  • Family history analysis of six kindreds with diagnosed cholelithiasis.
  • Examination of parental, offspring, and grandchild generations for gallstones and related comorbidities.
  • Identification of comorbidities including exogenous obesity, diabetes mellitus, lipid abnormalities, and hyperuricemia.

Purpose:

  • To investigate the familial aggregation of cholelithiasis and its associated metabolic risk factors.
  • To explore potential inherited or shared environmental influences on gallstone formation and related conditions.
  • To document the prevalence of cholelithiasis and comorbidities across multiple generations within affected families.

Summary:

  • Cholelithiasis was prevalent in parents (6/6 families), children (17/21), grandchildren (13/18), and great-grandchildren (1/unknown).

Related Experiment Videos

  • Comorbidities such as exogenous obesity, diabetes mellitus, and lipid abnormalities were frequently observed alongside cholelithiasis across generations.
  • Specific combinations of cholelithiasis with obesity, diabetes, and lipid abnormalities showed a pattern of inheritance or familial clustering.

    • Impact:

    • Highlights the potential hereditary component or shared environmental factors contributing to gallstone disease.
    • Suggests the importance of family history in assessing risk for cholelithiasis and associated metabolic disorders.
    • Provides data for further research into the genetic and environmental etiology of gallstone formation and related conditions.