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[Bioessay with brine Artemia to predict antibacterial and pharmacologic activity]
C Sánchez1, M Gupta, M Vásquez
1Departamento de Farmacología en la Facultad de Medicina, Universidad de Panamá.
Revista Medica De Panama
|January 1, 1993
Abstract:
The Brine Shrimp Test (BST) is a simple and inexpensive method to test cytotoxity, to biodirect phytochemical fractionation of natural products and as a predictor for antitumor and pesticidal activity. In this work, the BST test, an antibacterial test and the rat hippocratic screening test were used on 25 plant extracts and fractions, to evaluate the correlation, if any, between the BST and the others. Preliminary results show that the BST is not a predictor of antibacterial activity nor the hippocratic screening test.