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[Anaphylactic reaction in streptokinase therapy]
H Hohage1, B Schulte, B Pfeiff
1Institut für Pharmakologie und Toxikologie, RWTH Aachen, Bundesrepublik Deutschland.
Wiener Klinische Wochenschrift
|January 1, 1993
Summary
This case report details a patient experiencing an anaphylactic reaction to streptokinase, a common thrombolytic drug. The study highlights delayed IgG antibody development as a potential mechanism for allergic reactions to streptokinase.
Area of Science:
- Cardiology
- Immunology
- Pharmacology
Background:
- Streptokinase is a widely used thrombolytic agent for various thrombotic conditions.
- A significant drawback of streptokinase is its antigenicity, leading to allergic reactions.
- The precise mechanisms underlying streptokinase-induced allergic reactions remain incompletely understood.