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Peripheral epithelial odontogenic tumors

J G Batsakis¹, M J Hicks, C M Flaitz

¹Dept of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030.

The Annals of Otology, Rhinology, and Laryngology

|April 1, 1993

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Peripheral epithelial odontogenic tumors are rare extraosseous tumors, often originating in the gingiva. Ameloblastoma is the most common type, exhibiting a benign and nonaggressive clinical course.

Area of Science:

Oral pathology
Odontogenic neoplasms
Gnathic tumors

Background:

Peripheral epithelial odontogenic tumors (PEOTs) are the external counterparts of central gnathic odontogenic tumors.
These tumors develop in the mandibular or maxillary gingiva, originating from surface mucosa or dental lamina rests.

Purpose of the Study:

To describe the nature and behavior of peripheral epithelial odontogenic tumors.
To highlight the most common histologic type and its clinical course.

Main Methods:

Review of literature on peripheral epithelial odontogenic tumors.
Analysis of clinical and histological characteristics.

Main Results:

Ameloblastoma is identified as the most frequent histologic subtype of PEOTs.

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All peripheral epithelial odontogenic tumors demonstrate a benign, nonaggressive clinical progression.

Conclusions:

Peripheral epithelial odontogenic tumors are distinct entities with a favorable prognosis.
Understanding their origin and behavior is crucial for accurate diagnosis and management.