Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Dynamic cranial CT in ischemic cerebral lesions]

C Rozeik1, O Kotterer, A Wieschen

  • 1Radiologie I, Strahleninstitut der Städtischen Kliniken Darmstadt.

Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|April 1, 1993
PubMed
Summary

Dynamic CT effectively detects cerebral perfusion abnormalities in patients with carotid stenosis and neurologic deficits. It identifies infarcts early, even before morphological changes appear, aiding diagnosis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pantothenate kinase-associated neurodegeneration (PKAN) in a child with Down syndrome. A case report and follow-up with MRI.

BJR case reports·2018
Same author

Transarterial chemoembolization of liver metastases in patients with uveal melanoma.

European journal of radiology·2009
Same author

Prospective investigation of autonomic cardiac neuropathy in diabetes mellitus.

Clinical autonomic research : official journal of the Clinical Autonomic Research Society·2002
Same author

Angiographic pseudolesion in the liver in asymptomatic subacute cholecystitis.

European radiology·2001
Same author

[Intra-abdominal desmoplastic small-cell tumor--the rare differential diagnosis of a malignant peritoneal tumor].

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin·1998
Same author

[A late manifestation of chronic septic granulomatosis in a heterozygote carrier].

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin·1994

Area of Science:

  • Neurology
  • Radiology
  • Neuroimaging

Background:

  • Carotid stenosis is a significant risk factor for cerebrovascular events.
  • Accurate assessment of cerebral perfusion is crucial for diagnosing and managing neurologic deficits.
  • Early detection of perfusion abnormalities can improve patient outcomes.

Purpose of the Study:

  • To evaluate the utility of dynamic computed tomography (CT) in assessing cerebral perfusion in patients with neurologic deficits and carotid stenosis.
  • To correlate dynamic CT findings with the presence of cerebral infarcts and transient ischemic attacks (TIAs).
  • To compare dynamic CT findings with technetium-99m-labeled hexamethylpropyleneamine oxime single-photon emission computed tomography (99mTc-HMPAO-SPECT).

Main Methods:

  • Dynamic CT was performed at the level of the internal capsule in 58 patients with recent transient or permanent neurologic deficits and proven carotid stenoses.

Related Experiment Videos

  • Time/density curves were analyzed to assess cerebral perfusion.
  • Findings were correlated with the presence of cerebral infarcts, TIAs, and carotid stenosis severity.
  • Comparison with 99mTc-HMPAO-SPECT results was conducted.

    • Main Results:

    • Dynamic CT showed marked delay and reduced peaks in time/density curves in the presence of cerebral infarcts.
    • Abnormal perfusion was detectable by dynamic CT before morphological changes were evident.
    • Transient ischemic attacks (TIAs) did not show significant perfusion changes, while carotid stenosis results were variable.
    • Perfusion abnormalities identified by dynamic CT were partially confirmed by 99mTc-HMPAO-SPECT.

    Conclusions:

    • Dynamic CT is a valuable tool for detecting cerebral perfusion abnormalities in patients with neurologic deficits and carotid stenosis.
    • It allows for early identification of infarcts and can detect perfusion deficits prior to morphological changes.
    • Dynamic CT findings show partial agreement with 99mTc-HMPAO-SPECT, suggesting its complementary role in neuroimaging.