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Age-related changes in the hemostatic system

R Abbate, D Prisco, C Rostagno

    International Journal of Clinical & Laboratory Research
    |January 1, 1993
    PubMed
    Summary
    This summary is machine-generated.

    Aging significantly alters the hemostatic system, increasing risks for arterial thromboembolism in older adults. Key changes include elevated clotting factors and impaired fibrinolysis, contributing to a hypercoagulable state.

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    Area of Science:

    • Gerontology
    • Hematology
    • Cardiovascular Medicine

    Background:

    • Arterial thromboembolism incidence rises with age, necessitating research into age-related hemostatic system changes.
    • Epidemiological studies identify elevated fibrinogen, factor VII, and factor VIII as thrombotic disease risk factors in the elderly.