Related Experiment Video
Updated: Jul 28, 2026

Microbiological Rapid On-Site Evaluation for Pulmonary Infectious Diseases
Published on: March 1, 2024
[Personal experience with the use of Rulid (roxithromycin) in children less than 1 year of age]
1Detská klinika Nemocnice F. D. Roosevelta, Banská Bystrica.
Insights
Roxithromycin (Rulide) effectively treated infections in infants under 12 months old. Most children showed positive clinical responses with minimal side effects, demonstrating its safety and efficacy in this young population.
Area of Science:
- Pediatric infectious diseases
- Clinical pharmacology
- Antibiotic therapy
Abstract:
The authors give an account of the use of Roxithromycin (preparation Rulide) in children of the youngest age group, i.e. in infants. From January 1989 to April 1992 they treated 24 children under 5 weeks to 12 months of age with Roxithromycin. Roxithromycin was administered in amounts from 5 to 10 mg/kg after 12-hour intervals in the course of 4 to 12 days. In 22 children a favourable clinical effect was observed, in two children antibiotic treatment had to be changes because there was no clinical response. Undesirable effects, i.e. vomiting, during Roxithromycin were observed only in two children. In no instance was it necessary to discontinue treatment.
Related Concept Videos
Factors Affecting Drug Response: Overview
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Pharmacokinetics in Pediatric Patients: Drug Excretion