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[Multiple synchronous colorectal carcinomas]
R Pricolo1, P Salvatori, E Rizzitelli
1Divisione di Chirurgia Generale, Ospedale Civile, Casalpusterlengo, Milano.
Minerva Chirurgica
|February 1, 1993
Summary
Patients with colon cancer often have multiple tumors or other cancers. A thorough pre-operative examination is crucial for identifying all malignancies, including synchronous and metachronous extracolonic cancers.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Diagnostic Imaging
Background:
- Colorectal cancer diagnosis and management.
- Prevalence of multiple and extracolonic malignancies in colon cancer patients.
- Importance of comprehensive pre-operative evaluation.
Purpose of the Study:
- To investigate the incidence of multiple synchronous colon cancers.
- To identify co-occurring extracolonic malignancies in colon cancer patients.
- To propose criteria for differentiating multiple versus multifocal colon cancers.
Main Methods:
- Retrospective analysis of 118 colon cancer patients operated between 1986-1990.
- Pre-operative work-up including Barium enema, colonoscopy, and abdominal ultrasound.
- Specific tests for female patients: PAP-test and mammogram.
Main Results:
- Identified 7 cases (5.9%) of multiple synchronous colon cancer.
- Detected extracolonic malignancy in 3 patients (1 synchronous, 2 metachronous).
- Proposed new criteria to distinguish multiple from multifocal colon cancers.
Conclusions:
- Colon cancer patients have a significant risk of multiple synchronous and extracolonic malignancies.
- Comprehensive pre-operative colon examination is essential for all colorectal cancer patients.
- Screening for extracolonic malignancies should be considered in the pre-operative work-up.