Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prefabricated flaps using tissue expanders: an experimental study in rats

K Homma1, T Ohura, T Sugihara

  • 1Department of Plastic and Reconstructive Surgery, School of Medicine, Hokkaido University, Sapporo, Japan.

Plastic and Reconstructive Surgery
|May 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum: Centrality-Dependent Modification of Jet-Production Rates in Deuteron-Gold Collisions at sqrt[s_{NN}]=200  GeV [Phys. Rev. Lett. 116, 122301 (2016)].

Physical review letters·2025
Same author

Disentangling Centrality Bias and Final-State Effects in the Production of High-p_{T} Neutral Pions Using Direct Photon in d+Au Collisions at sqrt[s_{NN}]=200  GeV.

Physical review letters·2025
Same author

Measurement of Direct-Photon Cross Section and Double-Helicity Asymmetry at sqrt[s]=510  GeV in p[over →]+p[over →] Collisions.

Physical review letters·2023
Same author

Probing Gluon Spin-Momentum Correlations in Transversely Polarized Protons through Midrapidity Isolated Direct Photons in p^{↑}+p Collisions at sqrt[s]=200  GeV.

Physical review letters·2021
Same author

Erratum: Evolution of π^{0} Suppression in Au+Au Collisions from sqrt[s_{NN}]=39 to 200 GeV [Phys. Rev. Lett. 109, 152301 (2012)].

Physical review letters·2020
Same author

Nuclear Dependence of the Transverse Single-Spin Asymmetry in the Production of Charged Hadrons at Forward Rapidity in Polarized p+p, p+Al, and p+Au Collisions at sqrt[s_{NN}]=200  GeV.

Physical review letters·2019

Tissue expansion significantly improves muscle vascularized pedicle flap survival in rats. Expanded flaps showed greater survival area compared to non-expanded or Biobrane-covered flaps, indicating enhanced vascularity.

Area of Science:

  • Plastic Surgery
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Muscle vascularized pedicle flaps (MVP flaps) are crucial in reconstructive surgery.
  • Optimizing flap survival area is essential for successful tissue transplantation.
  • The role of tissue expansion in enhancing flap viability requires further investigation.

Purpose of the Study:

  • To compare the survival area of MVP flaps raised in expanded versus non-expanded tissue in a rat model.
  • To evaluate the efficacy of tissue expanders in promoting flap survival.

Main Methods:

  • Rats were divided into three groups: tissue expander (expanded and non-expanded) and Biobrane control.
  • MVP flaps were elevated, and their survival area was measured.
  • Microangiography was used to assess vascularity.

Related Experiment Videos

Main Results:

  • Group I (expanded tissue) demonstrated a significantly higher mean flap survival area (96.6%) compared to Group II (non-expanded, 73.2%) and Group III (Biobrane, 59.5%).
  • Microangiography revealed increased vascularity within the pedicle of expanded flaps.
  • Statistical analysis confirmed significant differences in flap survival between groups (p < 0.05).

Conclusions:

  • Tissue expansion significantly enhances the survival area of muscle vascularized pedicle flaps in rats.
  • The mechanism behind improved flap survival appears to be related to increased vascularity within the flap pedicle.
  • These findings suggest tissue expansion is a promising strategy for improving reconstructive surgery outcomes.