[Fracture incidence in 803 women with postmenopausal osteoporosis under drug treatment]

In a survey of cases of confirmed postmenopausal osteoporosis, 803 women were asked to complete a questionnaire on radiologically confirmed fractures sustained prior to and during drug therapy. Under monotherapy (fluoride or calcium, n = 92) the number of peripheral and central fractures was 54% and 49% lower, respectively. The corresponding figures with two substances (fluoride and calcium, n = 226) were 58% and 60%, with three substances (fluoride, calcium and estrogens or Vitamin D, n = 223) 83% and 72%, and with four substances (n = 254) 85% and 75%.