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[Medicinal reduction of mechanical hemolysis]
Abstract:
The mechanical resistance of erythrocytes after gas dispersion (oxygen, resp. mixed oxygen/carbon dioxide) and treatment in the hemoresistometer was studied on human conserved fresh blood under in-vitro conditions. Xylocitin (Lidocain) was tested as to memebrane stabilizing capability. It was found that test doses of about 5 mg and 40 mg per 100 ml of heparinized fresh blood result in an increased resistance of erythrocytes against mechanical trauma.