Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Nevus spilus. A histopathological study (author's transl)]

H J Cramer

    Zentralblatt Fur Allgemeine Pathologie U. Pathologische Anatomie
    |January 1, 1977
    PubMed
    Summary

    Nevus spilus, a pigmented macule with darker speckles, is likely a café-au-lait nevus associated with neurofibromatosis. Histopathological analysis reveals varied structures within the darker spots, indicating it

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Do Varicosan bandages really rarely cause contact eczema? Case report of allergic contact dermatitis caused by propyl hydroxybenzoate following the use of Varicosan bandages].

    Dermatologische Monatschrift·1989
    Same author

    ["Precancerous penile papules" and a "benign penile papillomatosis"].

    Zeitschrift fur Urologie und Nephrologie·1981
    Same author

    [Melanophagocytoma].

    Dermatologische Monatschrift·1981
    Same author

    [Enzyme histochemical study of dermatofibrosarcoma protuberans - tumor of neural connective tissue].

    Dermatologische Monatschrift·1981
    Same author

    [The black hidrocystoma (Monfort)].

    Dermatologische Monatschrift·1980
    Same author

    [Chronic vulvar pruritus caused by terminal-fibre neuroma episiotomy scar (author's transl)].

    Zentralblatt fur Gynakologie·1980

    Area of Science:

    • Dermatology and Pathology
    • Genetics and Oncology

    Context:

    • The interpretation of nevus spilus has evolved, with a modern definition focusing on clinical diagnostics.
    • Previous definitions lacked histopathological clarity, prompting further investigation into its nature.
    • The association with neurofibromatosis type 1 (NF1) requires detailed histopathological correlation.

    Purpose:

    • To histopathologically analyze the distinct darker spots within nevus spilus lesions.
    • To clarify the diagnostic criteria and underlying pathology of nevus spilus.
    • To determine if nevus spilus represents a distinct clinicopathological entity.

    Summary:

    • A review of literature and current study suggest nevus spilus is likely a café-au-lait nevus in neurofibromatosis-type patients.
    • The darker speckles within nevus spilus exhibit diverse histopathological structures.
    • These structures include nevus cell nevi, nevoid lentigines, epidermal pigmented macules, or post-inflammatory pigment changes.

    Impact:

    • This research refines the understanding of nevus spilus, differentiating it from a standalone entity.
    • It highlights the importance of histopathological examination for accurate diagnosis and patient management.
    • The findings aid in the early identification and management of neurofibromatosis-type conditions.

    Related Experiment Videos