Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sequence of a cDNA encoding bovine apolipoprotein H

B Gao1, M Virmani, E Romm

  • 1Laboratory of Physiological and Pharmacological Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892.

Gene
|April 30, 1993
PubMed
Summary

The bovine apolipoprotein H (ApoH) gene sequence was identified. This bovine ApoH shows high sequence similarity to human and rat ApoH, aiding comparative studies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transient Large-Scale Anisotropy in TeV Cosmic Rays due to an Interplanetary Coronal Mass Ejection.

Physical review letters·2026
Same author

First Detection of Ultrahigh Energy Emission from Gamma-Ray Binary LS I +61° 303.

Physical review letters·2026
Same author

Evidence of Cosmic-Ray Acceleration up to Sub-PeV Energies in the Supernova Remnant IC 443.

Physical review letters·2026
Same author

Precise Measurement of the Cosmic Ray Helium Spectrum above 0.1 PeV.

Physical review letters·2026
Same author

All-Sky Search for Individual Primordial Black Hole Bursts with LHAASO.

Physical review letters·2025
Same author

Rucaparib maintenance for newly diagnosed advanced ovarian cancer: interim overall survival, progression-free survival, and safety at 5 years of follow-up from the phase III ATHENA-MONO/GOG-3020/ENGOT-ov45 study.

Annals of oncology : official journal of the European Society for Medical Oncology·2025

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Genomics

Background:

  • Apolipoprotein H (ApoH) plays a crucial role in lipid metabolism and immune regulation.
  • Understanding the genetic basis of ApoH across species can reveal conserved functions and evolutionary insights.

Purpose of the Study:

  • To determine the nucleotide sequence of the bovine apolipoprotein H (ApoH) cDNA.
  • To analyze the structural and evolutionary relationship of bovine ApoH with its counterparts in other species.

Main Methods:

  • Nucleotide sequencing of the bovine ApoH cDNA.
  • Bioinformatic analysis to deduce protein sequence and compare homology.

Main Results:

  • The complete nucleotide sequence for bovine ApoH cDNA was successfully determined.

Related Experiment Videos

  • The deduced bovine ApoH protein consists of a 19-amino acid signal peptide and a 326-amino acid mature protein.
  • Bovine ApoH exhibits significant homology, with 89% and 86% similarity to human and rat ApoH, respectively.

    • Conclusions:

    • The determined bovine ApoH sequence provides a valuable resource for further functional and comparative studies.
    • High homology suggests conserved functional roles of ApoH in mammals.