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Related Experiment Videos

Anthelmintic resistance

T M Craig1

  • 1Department of Veterinary Pathobiology, Texas A&M University, College Station 77843.

Veterinary Parasitology
|February 1, 1993
PubMed
Summary
This summary is machine-generated.

Anthelmintic resistance in livestock worms is a growing problem, particularly in horses and small ruminants. Understanding and managing this resistance is crucial for effective parasite control in grazing animals.

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Area of Science:

  • Veterinary Parasitology
  • Animal Health
  • Drug Resistance

Background:

  • Anthelmintics are the primary method for controlling helminths in livestock.
  • Worm populations can develop resistance to anthelmintics, leading to treatment failures.
  • Anthelmintic resistance is most prevalent in equids and small ruminants due to frequent drug use.

Purpose of the Study:

  • To highlight the issue of anthelmintic resistance in livestock helminths.
  • To discuss the mechanisms and implications of anthelmintic resistance.
  • To provide insights into managing and delaying the onset of resistance.

Main Methods:

  • Review of existing literature on anthelmintic resistance in various livestock species.
  • Analysis of resistance patterns in different geographic locations and host-parasite combinations.

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  • Evaluation of treatment strategies and their impact on resistance development.

    • Main Results:

    • Widespread resistance of benzimidazole/phenothiazine by small strongyles in horses.
    • Verified resistance in Haemonchus, Teladorsagia, and Trichostrongylus against multiple anthelmintic classes in small ruminants.
    • Reported failure of levamisole against Ostertagia ostertagi in cattle.

    Conclusions:

    • Anthelmintic resistance is a farm-specific issue requiring tailored management strategies.
    • Rapid drug rotation and epidemiological treatments can accelerate or slow resistance, respectively.
    • Integrated approaches combining strategic treatments, tactical interventions, and drug evaluation are essential for sustainable parasite control and livestock production.