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Phase I study of amonafide dosing based on acetylator phenotype

M J Ratain1, R Mick, F Berezin

  • 1Department of Medicine, University of Chicago Pritzker School of Medicine, Illinois 60637.

Cancer Research
|May 15, 1993
PubMed
Summary

Determining the correct amonafide dose is crucial for cancer patients. This study recommends specific phase II doses for fast and slow acetylators to minimize toxicity and maximize efficacy.

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