Related Experiment Video
Updated: Jul 12, 2026

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
Published on: June 14, 2014
A human pseudoautosomal gene encodes the ANT3 ADP/ATP translocase and escapes X-inactivation
R Slim1, J Levilliers, H J Lüdecke
1Unité de Génétique Moléculaire Humaine (CNRS URA 1445), Institut Pasteur, Paris, France.
Abstract:
We report that the human ANT3 ADP/ATP translocase gene is a pseudoautosomal gene located proximal to the GM-CSF receptor alpha chain gene (CSF2RA). An ANT3-homologous locus, likely corresponding to a pseudogene, maps to chromosome 9. The ANT3 gene is transcribed from the centromere to the telomere and contains in its first intron a CpG island mapped 1300 kb from the telomere. This gene is transcribed from the Y chromosome and from the active and inactive X chromosomes. This gene thus escapes X-inactivation as predicted for genes belonging to the pseudoautosomal region.
Related Concept Videos
X-Inactivation
Inheritance of Chromatin Structures
Non-LTR Retrotransposons
The Ratio of X Chromosome to Autosomes
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...
X-inactivation
Exon Recombination
Exon shuffling follows “splice frame rules.” Each exon has three reading...

