Related Experiment Videos
Invasive lobular carcinoma. Imaging features and clinical detection
M A Helvie1, C Paramagul, H A Oberman
1Department of Radiology, University of Michigan Medical Center, Ann Arbor.
Investigative Radiology
|March 1, 1993
Summary
Mammography detects invasive lobular carcinoma (ILC) in 92% of cases, often as irregular masses. Infrequent microcalcifications can challenge detection, highlighting the complementary roles of mammography and physical exams for breast cancer diagnosis.
Area of Science:
- Radiology
- Oncology
- Breast Imaging
Background:
- Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.
- Mammographic detection of ILC can be challenging due to its unique presentation.
Purpose of the Study:
- To report mammographic findings and detection methods for invasive lobular carcinoma.
- To analyze the characteristics of ILC on mammograms.
Main Methods:
- Retrospective review of preoperative mammograms and clinical records.
- Analysis of 52 cases of ILC diagnosed between 1979-1991.
Main Results:
- Abnormal mammographic findings were present in 92% of ILC cases.
- Common findings included irregular spiculated masses (63%), asymmetric densities (13%), and architectural distortion (10%).
- Microcalcifications were infrequent (4%), contrasting with ductal carcinoma.
Conclusions:
- The low rate of microcalcifications in ILC may impede mammographic detection.
- Mammography and breast physical examination are complementary tools for ILC detection.
- Early detection of ILC is crucial for patient outcomes.