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The Canadian Labour Force Ten Percent Sample Study. Cancer mortality among men, 1965-1979
J P Lindsay1, K M Stavraky, G R Howe
1Bureau of Chronic Disease Epidemiology, Health and Welfare Canada, Toronto.
Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association
|April 1, 1993
Summary
This study analyzed cancer mortality in Canadian workers, identifying 23 key occupational cancer associations. Four links suggest smoking/alcohol as causes, while seven warrant further investigation for lung and stomach cancers.
Area of Science:
- Occupational Health
- Epidemiology
- Cancer Research
Background:
- The Canadian Labour Force 10% Sample Study cohort was updated for mortality data through 1979.
- Occupational and industrial data from 1965-1969 were linked to mortality records.
Purpose of the Study:
- To investigate cancer mortality risks associated with specific occupations and industries.
- To identify potential occupational cancer clusters and inform public health interventions.
Main Methods:
- Computerized record linkage matched 415,309 men's employment data to the Canadian National Mortality Data Base.
- Analysis focused on 9,739 cancer deaths between 1965-1979 across 274 occupations and 294 industries.
- Identified associations with relative risk > 1.0, considering strength, dose-response, and consistency.
Main Results:
- 243 significant occupational cancer associations were found.
- 23 associations were deemed of particular interest.
- Four associations (e.g., bartenders and pharyngeal cancer) linked to smoking/alcohol; seven (e.g., carpenters and stomach cancer) showed biological plausibility or literature support.
Conclusions:
- Identified specific occupations with elevated cancer risks, potentially linked to lifestyle factors or workplace exposures.
- Findings suggest targeted intervention strategies for high-risk occupations.
- Further research is recommended for several occupation-specific cancer associations.
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