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[Adverse effect of prolonged formalin fixation on DNA ploidy in paraffin-embedded tissue]
N Ichikawa1, E Okamoto, J Fujimoto
1First Dept. of Surgery, Hyogo College of Medicine.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|April 1, 1993
Abstract:
From retrospective analysis of 174 formalin fixed, paraffin-embedded, HCC tissue samples, the possible correlation was investigated between the CV determined by FCM and the duration of formalin fixation. An adverse effect of prolonged formalin fixation on CV and fluorescence intensity in liver tissue was investigated prospectively in samples from 4 patients.