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Related Experiment Video

Updated: Jul 27, 2026

Surgical Method for Virally Mediated Gene Delivery to the Mouse Inner Ear through the Round Window Membrane

Surgical Method for Virally Mediated Gene Delivery to the Mouse Inner Ear through the Round Window Membrane

Published on: March 16, 2015

Congenital rubella deafness: a preventable disease

C S Peckham, J A Martin, W C Marshall

Lancet (London, England)

|February 3, 1979

Summary

Congenital rubella is a significant cause of sensorineural deafness in young children. Increased rubella vaccination is crucial to prevent this serious defect.

Area of Science:

Pediatrics
Otolaryngology
Immunology

Background:

Congenital rubella infection can lead to severe developmental issues, including sensorineural deafness.
Early identification and intervention are critical for children with hearing impairments.

Purpose of the Study:

To investigate the prevalence of rubella antibody in children under 4 with sensorineural deafness.
To identify risk factors associated with rubella-induced deafness in young children.

Main Methods:

An unselected cohort of 568 children under 4 years old was studied between 1972-1975.
Rubella antibody testing was performed on children attending the Nuffield Hearing and Speech Centre.
Children were categorized based on the presence or absence of sensorineural deafness.

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Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

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Last Updated: Jul 27, 2026

Surgical Method for Virally Mediated Gene Delivery to the Mouse Inner Ear through the Round Window Membrane

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Published on: March 16, 2015

Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research

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Published on: June 8, 2017

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

Published on: February 29, 2020

Main Results:

Sensorineural deafness was diagnosed in 349 children; 24% had rubella antibody.
Only 9% of children without deafness had rubella antibody.
Significant differences in family history, maternal rubella, perinatal events, and other defects were observed between seropositive and seronegative deaf children.

Conclusions:

Congenital rubella is a notable cause of sensorineural deafness in children.
Vigorous pursuit of rubella vaccination programs is essential for future defect prevention.