Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Per-urethral transvesical first-trimester amniocentesis

R Frydman¹, J C Pons, E Borghi

¹Service de Gynécologie-Obstétrique, Hopital Antoine Béclère, Clamart, France.

European Journal of Obstetrics, Gynecology, and Reproductive Biology

|February 1, 1993

Summary

Early amniocentesis via a per-urethral transvesical route is feasible before 13 weeks gestation. This method offers a potential alternative to transabdominal amniocentesis for obtaining amniotic fluid samples.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effect of docosahexaenoic acid as an anti-inflammatory for Caco-2 cells and modulating agent for gut microbiota in children with obesity (the DAMOCLE study).

Journal of endocrinological investigation·2024

Same author

Developing a cell-bound detection system for the screening of oxidase activity using the fluorescent peroxide sensor roGFP2-Orp1.

Protein engineering, design & selection : PEDS·2020

Same author

Phenylketonuric diet negatively impacts on butyrate production.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2018

Same author

Microbiologic and clinical characteristics of biofilm-forming Candida parapsilosis isolates associated with fungaemia and their impact on mortality.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2017

Same author

Efficacy of non-invasive mechanical ventilation in the general ward in patients with chronic obstructive pulmonary disease admitted for hypercapnic acute respiratory failure and pH < 7.35: a feasibility pilot study.

Internal medicine journal·2015

Same author

Randomized, controlled, open-label, non-inferiority study of the CONSORT algorithm for individualized dosing of follitropin alfa.

Reproductive biomedicine online·2015

Area of Science:

Obstetrics and Gynecology
Fetal Medicine
Minimally Invasive Procedures

Background:

Early amniocentesis is crucial for genetic testing and fetal assessment.
The transabdominal route is the conventional method for amniocentesis.
Minimally invasive techniques are sought to improve safety and accessibility.

Purpose of the Study:

To evaluate the feasibility of early amniocentesis using a per-urethral transvesical approach.
To assess the ease of amniotic fluid acquisition and successful cell culture via this route.
To determine if this method is a viable alternative to the transabdominal route.

Main Methods:

Eight patients undergoing elective pregnancy termination provided amniotic fluid samples.
A per-urethral transvesical technique was employed for fluid collection before 13 weeks gestation.

Related Experiment Videos

Amniotic fluid volume was recorded, and samples were cultured.

Main Results:

Amniotic fluid was successfully obtained in all eight cases.
The average amniotic fluid volume collected was 12.5 +/- 7.8 ml.
Successful cell culture was achieved in all samples, with one successful culture from only 2 ml of fluid.

Conclusions:

Early amniocentesis before 13 weeks gestation is feasible using the per-urethral transvesical route.
This technique allows for easy acquisition of amniotic fluid and successful cell culture.
Further clinical trials are recommended to compare the per-urethral transvesical route with the transabdominal route.