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Well-differentiated liposarcoma mimicking a pleomorphic lipoma--a case report
1Department of Oral Pathology, Faculty of Stomatology, University of Belgrade, Serbia, Yugoslavia.
Summary
A rare case of well-differentiated liposarcoma, a type of cancer, was identified in a woman with a supraclavicular mass. The tumor initially resembled a benign pleomorphic lipoma but was confirmed as liposarcoma through detailed microscopic analysis.
Area of Science:
- Oncology
- Pathology
- Surgical Oncology
Background:
- Liposarcomas are malignant tumors arising from fat cells.
- Well-differentiated liposarcoma is the least aggressive subtype.
- Distinguishing benign lipomatous tumors from low-grade liposarcomas can be challenging on initial biopsy.
Observation:
- A 59-year-old woman presented with a supraclavicular mass.
- Initial biopsy sections showed features suggestive of pleomorphic lipoma.
- The mass contained floret-like multinucleated giant cells.
Findings:
- Multiple microscopic sections confirmed the diagnosis of well-differentiated liposarcoma.
- The presence of pathognomonic features confirmed malignancy despite initial benign appearance.
- Floret-like multinucleated giant cells are a key feature in this case.
Implications:
- Accurate diagnosis of well-differentiated liposarcoma is crucial for appropriate patient management.
- Histopathological review with multiple sections is vital for definitive diagnosis.
- This case highlights the importance of recognizing subtle malignant features in lipomatous tumors.